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RAS/RAS-RAF-IN-1 is a potent inhibitor of both RAS and RAS-RAF pathways. It demonstrates a KD of 5.0 μM-15 μM for cyclophilin A (CYPA) binding affinity and exhibits antitumor activity.
Potent inhibitor of Ras and Raf.
Exhibits antitumor activity.
EC50 of 0.5 μM-5.0 μM for BRAF-GTP-KRAS-G12C disruption.
IC50 of 1.0 μM-10 μM for pERK inhibition in H358 cells.
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Gastric lipase is a recombinant human gastric (triacylglycerol) lipase produced in HEK293 cells and supplied as a His-tagged solution for research use. It catalyzes the hydrolysis of dietary triglycerides into free fatty acids and glycerol and is useful for biochemical assays, digestion studies, and enzyme characterization.
Recombinant human enzyme with native-like glycosylation
Expressed in HEK293 cells for improved folding and activity
C-terminal His tag for detection and purification
High purity (>95%) confirmed by reducing SDS-PAGE
Supplied as a ready-to-use solution in multiple size formats
Observed molecular weight ~48-50 kDa due to glycosylation
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BCMA Biosimilar Antibody is a biosimilar antibody with human reactivity produced in humanized Available in 100 ug size with 7 - 14 business days lead time Ships via gel pack Store at -20 C to -80 C for 12 months in lyophilized form After reconstitution if not intended for use within a month aliquot and store at -80 C (Avoid repeated freezing and thawing) Lyophilized antibodies are shipped at ambient temperature
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Neutral protease, Paenibacillus polymyxa is a bacterial neutral metalloprotease used in research to selectively cleave extracellular matrix proteins such as fibronectin and type IV collagen. Supplied as a white to off-white solid, it is commonly used for tissue dissociation, separation of epidermis from dermis, and release of intact epithelial sheets in culture. Refer to the certificate of analysis for recommended storage and specific activity data.
Neutral metalloprotease active against fibronectin and type IV collagen.
Suitable for tissue dissociation and separation of epidermis from dermis.
Enzyme activity ≥ 0.5 U/mg (solid), unit definition provided.
White to off-white solid formulation for laboratory use.
Shipped at room temperature; follow COA for storage conditions.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
MK-0941 is an orally active, allosteric glucokinase activator supplied for preclinical research into glucose regulation and type 2 diabetes. It increases insulin secretion and glucose uptake and is used in in vitro enzyme assays and in vivo pharmacology studies to evaluate glucokinase modulation.
Orally active, allosteric glucokinase activator for mechanism studies.
High reported purity suitable for analytical and biological assays.
Available in small milligram quantities for preclinical work.
Offered as solid and as DMSO solution formats for flexible dosing.
Storage guidance included for solid and solvent preparations.
Structural and chemical identifiers provided for reproducibility.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Protein kinase inhibitor H-7 dihydrochloride is a small-molecule serine/threonine kinase inhibitor commonly used to inhibit protein kinase C and related kinases in biochemical and cell-based assays. It is supplied as a solid with high reported purity for research applications.