Protein Purification
Abcam (+)-Nutlin-3, p53-MDM2 binding inhibitor, 25MG
MW 581.5 Da, Purity >98%. p53-MDM2 binding inhibitor (IC₅₀ = 13 μM). Less potent enantiomer of (-)-Nutlin-3 (Asc-4428
The product is subject to the following: Abcam Restricted Use Statement
Abcam LYS6K2, S6 kinase inhibitor, 5MG
MW 445.42 g/mol. Selective, cell-permeable S6 kinase inhibitor. Blocks phosphorylation of p70 ribosomal S6 kinase.
The product is subject to the following: Abcam Restricted Use Statement
Abcam PQ 401, Cell-permeable IGF1R inhibitor, 10MG
MW 341.8 Da, Purity >99%. Cell-permeable IGF1R inhibitor (IC₅₀ = 12 μM for IGF-stimulated autophosphorylation). Shows antiproliferative effects against MCF-7 breast cancer cells. Induces renal hypertrophy in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Paro x etine hydrochloride, 5-HT uptake inhibitor, 10MG
MW 365.8 Da, Purity >99%. Potent, selective 5-HT (serotonin) uptake inhibitor. Inhibits human and rat 5-HT transporters (Ki values are 0.065 and 0.05 nM, respectively). Antidepressant and anxiolytic in vivo.
The product is subject to the following: Abcam Restricted Use Statement